Ometto started his scientific work with a focus on biogeochemistry, stable isotopes and interactions among the components of the biosphere, including “anthropic landscapes”.
His recent academic and research activities are centered on the diagnosis and prognosis of anthropogenic activities and climatic changes, in natural biogeochemical processes, land use and land cover, greenhouse gas emissions and sustainability indicators; with contributions to the Brazilian government on issues related to the quantification of carbon emissions of the LULUCF sector.