International Union of Immunological Societies (IUIS) ti dasilẹ ni May 1969. Awọn ibi-afẹde rẹ ni lati: ṣeto ifowosowopo agbaye ni ajẹsara ati lati ṣe agbega ibaraẹnisọrọ laarin awọn ẹka oriṣiriṣi ti ajẹsara ati awọn koko-ọrọ ti o ni ibatan; ṣe iwuri laarin ifowosowopo agbegbe ominira kọọkan ti imọ-jinlẹ laarin awọn awujọ ti o ṣe aṣoju awọn iwulo ti ajẹsara; ati ki o ṣe alabapin si ilọsiwaju ti ajẹsara ni gbogbo awọn aaye rẹ.
Ẹgbẹ naa lepa awọn ibi-afẹde wọnyi nipasẹ apejọ ti awọn apejọ International International Triennial ati iṣẹ ti Awọn igbimọ Akanse, nipa mimujuto ibatan pẹlu awọn ajọ agbaye miiran (fun apẹẹrẹ International Society of Immuno-pharmacology, International Society of Development and Comparative Immunology, International Association of Allergy). ati Imuniloji Iṣoogun, Awujọ fun Imunoloji Mucosal, Awujọ Kariaye fun Imunoloji ti Atunse ati Ajo Agbaye ti Ilera). O tun ṣe iwuri fun ifowosowopo agbegbe (gẹgẹbi nipasẹ European Federation of Immunological Societies, Latin American Association of Immunology, Federation of African Immunological Societies ati Federation of Immunological Societies of Asia-Oceania).
Ijọpọ ṣe alabapin ninu ọpọlọpọ awọn Igbimọ ISC; ie, idasile ti Ile-ifowopamọ Data Hybridoma labẹ CODATA jẹ apẹẹrẹ akiyesi kan. Ni lọwọlọwọ Ẹgbẹ naa ni, gẹgẹbi awọn ọmọ ẹgbẹ ti o faramọ, Awọn awujọ lati awọn agbegbe ominira ti imọ-jinlẹ 54 ti o nsoju ju 33,000 awọn ajẹsara ajẹsara agbaye.