Availability and insertion of meta-l and vitamin-derived cofactors are required for the correct structure and function of proteins, thus preventing severe pathological conditions, related to inborn errors of cofactor metabolism.
Methodologies aimed at experimentally predicting or describing the required interactions have allowed dissection of individual step of cofactor assembly, as well as the molecular consequences of alterations of individual steps.
This advanced school will focus on the fundamentals of cofactor biosynthesis, trafficking, and insertion by using either pure recombinant protein or more complex cell/organism models. Basic knowledge of these processes will be translated to pharmacology and pathophysiology.
The advanced school is primarily aimed at young scientists (PhD students, post-docs, junior faculty) active in the fields of biochemistry, chemistry, nutrition, and related disciplines.
The global vectors of uncertainty that will influence the outcomes of the COVID-19 pandemic: results of the regional experts' discussions
Call for emergency action to limit global temperature increases, restore biodiversity, and protect health
COVID-19’s ticking clock
What we are reading
A response to The Independent Panel for Pandemic Preparedness and Response’s new report on the international health response to the COVID-19 Pandemic
Mathematics for a better world
Introducing a new Member of the ISC: Institute for Global Environmental Strategies (IGES)
World Logic Day, 14 January
Statement on scientific freedom in Japan
What are your latest findings and strategies to address the COVID-19 crisis, including for vaccine deployment?
Global Young Academy promote sustainable solutions to problems within global health and higher education
The future of scientific publishing under the spotlight for ISC member organizations in Europe
Lessons from existing disaster risk and recovery research should inform equitable and sustainable pathways out of the pandemic
Small Island Developing States (SIDS) Liaison Committee appointed to strengthen links with the SIDS scientific community
Membership Notice Board
How to Become a Member
Keep us up-to-date
A planetary outlook for urban health
ISC commits to enhanced collaboration with UN-Habitat and UNDRR on urban health and wellbeing and disaster risk reduction
Wellbeing in the Digital Age: INGSA report on the effect of digital technologies on government, society and individual wellbeing
New report from scientific experts provides a unique guide to translate Sustainable Development Goals into reality
Membership Online Directory
ICSU’s Urban Health and Wellbeing Programme highlights importance of health issues at UNEP General Assembly
ICSU’s Urban Health programme convenes workshop in China on modelling approaches to human health risks in cities
Call for nominations: Scientific Committee for Health and Wellbeing in the Changing Urban Environment: a Systems Analysis Approach
Call for expressions of interest: Modeling urban health and wellbeing – communicating results for policy and action
Paper published on ICSU's programme on Health and Wellbeing in the Changing Urban Environment
Science Plan on Health and Wellbeing in the Changing Urban Environment – ICSU Regional Office for Asia & the Pacific
Final four Rio+20 policy briefs released
Ecosystem Change and Human Wellbeing
Towards a Systems Analysis Approach to Health and Wellbeing in the Changing Urban Environment